Porphyromonas gingivalis disturbs host–commensal homeostasis by changing complement function
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Porphyromonas gingivalis disturbs host–commensal homeostasis by changing complement function
Porphyromonas gingivalis is a Gram-negative anaerobic rod that has been proposed as an orchestrator of complement-dependent dysbiotic inflammation. This notion was suggested from its capacities to manipulate the complement-Toll-like receptor crosstalk in ways that promote dysbiosis and periodontal disease in animal models. Specifically, while at low colonization levels, P. gingivalis interferes...
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Porphyromonas gingivalis is implicated in the etiology of chronic periodontitis. Genotyping studies suggest that genetic variability exists among P. gingivalis strains; however, the extent of variability remains unclear and regions of variability remain largely unidentified. To assess P. gingivalis strain diversity, we previously used heteroduplex analysis of the ribosomal operon intergenic spa...
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ژورنال
عنوان ژورنال: Journal of Oral Microbiology
سال: 2017
ISSN: 2000-2297
DOI: 10.1080/20002297.2017.1340085